FAMILIAL HAEMOPHILIA AND FACTOR VII DEFICIENCY

Familial haemophilia and factor VII deficiency.

This investigation is reported because of the combination of familial haemophilia and factor VII deficiency and the unusual occurrence of a female haemophiliac. Cases of combined deficiencies of different clotting factors are extremely rare and up till now there have been reported combinations of haemo-but not of haemophilia and factor VII deficiency. Female haemophiliacs in the homozygous stat...

Jaundice and factor VII deficiency in newborn

Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...

Haemophilia A (Factor VIII Deficiency)

This is a bleeding disorder caused by deficiency of clotting factor VIII. The vast majority of cases are inherited but acquired forms do exist, largely in older patients, due to autoantibodies directed against factor VIII or haematological malignancy. [2] Severity of disease depends upon levels of remaining factor activity, with normal range expressed as 50-200% (refer to local laboratory for r...

Inherited factor VII deficiency

Haemophilia B (Factor IX Deficiency)

If a woman is a carrier there is a 1 in 2 chance that any son will be affected and a 1 in 2 chance that any daughter will be a carrier. If a man with the disease fathers a child, any daughter will be a carrier and any son will be unaffected and will not carry the gene. There is a report of a daughter of a man with the disease who had a factor IX level of 5% and haemarthroses and this was though...